What is a Neurofibroma?A Neurofibroma is a benign focal proliferation of peripheral nerve tissue.  It is usually skin-colored, pink or brown and can be flat, dome-shaped, or pedunculated.  They can be soft, firm, and sometimes tender.  In general, they begin to appear just before or during adolescence.  They tend to increase in size and number with age.  They are benign and do not carry an increased risk of developing malignant transformation.  However, they often represent a major cosmetic problem in adults.  Itching is also often associated with accelerated growth of the neurofibroma.  Treatment consists of excision of the lesion.  Neurofibromas most commonly develop in individuals who have Neurofibromatosis.

What is Neurofibromatosis?

A neurocutaneous disorder that is genetically inherited in an autosomal dominant fashion.  Two major forms of neurofibromatosis are recognized:  NF-1 (Von Recklinghausen disease) and NF-2.  Both are characterized by neurofibromas, in addition to other diagnostic criteria.